Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior

The extracellular matrix (ECM) is a major regulator of cell behavior. Recent studies have indicated the importance of the physical properties of the ECM, including its stiffness, for cell migration and differentiation. Using actomyosin-generated forces, cells pull the ECM and sense stiffness via cel...

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Bibliographic Details
Published in:PLoS One
Main Authors: Omachi, Tomohiro, Ichikawa, Takafumi, Kimura, Yasuhisa, Ueda, Kazumitsu, Kioka, Noriyuki
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384775/
https://ncbi.nlm.nih.gov/pubmed/28388663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175324
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