IGF1 regulates RUNX1 expression via IRS1/2: Implications for antler chondrocyte differentiation

Although IGF1 is important for the proliferation and differentiation of chondrocytes, its underlying molecular mechanism is still unknown. Here we addressed the physiologic function of IGF1 in antler cartilage and explored the interplay of IGF1, IRS1/2 and RUNX1 in chondrocyte differentiation. The r...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Cycle
Hauptverfasser: Yang, Zhan-Qing, Zhang, Hong-Liang, Duan, Cui-Cui, Geng, Shuang, Wang, Kai, Yu, Hai-Fan, Yue, Zhan-Peng, Guo, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384582/
https://ncbi.nlm.nih.gov/pubmed/28055425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1274471
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