IGF1 regulates RUNX1 expression via IRS1/2: Implications for antler chondrocyte differentiation

Although IGF1 is important for the proliferation and differentiation of chondrocytes, its underlying molecular mechanism is still unknown. Here we addressed the physiologic function of IGF1 in antler cartilage and explored the interplay of IGF1, IRS1/2 and RUNX1 in chondrocyte differentiation. The r...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Yang, Zhan-Qing, Zhang, Hong-Liang, Duan, Cui-Cui, Geng, Shuang, Wang, Kai, Yu, Hai-Fan, Yue, Zhan-Peng, Guo, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384582/
https://ncbi.nlm.nih.gov/pubmed/28055425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1274471
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