Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

Recent clinical studies indicate that adoptive T-cell therapy and especially chimeric antigen receptor (CAR) T-cell therapy is a very potent and potentially curative treatment for B-lineage hematologic malignancies. Currently, autologous peripheral blood T cells are used for adoptive T-cell therapy....

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Van Caeneghem, Yasmine, De Munter, Stijn, Tieppo, Paola, Goetgeluk, Glenn, Weening, Karin, Verstichel, Greet, Bonte, Sarah, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Debets, Reno, Vermijlen, David, Abken, Hinrich, Vandekerckhove, Bart
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384408/
https://ncbi.nlm.nih.gov/pubmed/28405508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1283460
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