Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

Recent clinical studies indicate that adoptive T-cell therapy and especially chimeric antigen receptor (CAR) T-cell therapy is a very potent and potentially curative treatment for B-lineage hematologic malignancies. Currently, autologous peripheral blood T cells are used for adoptive T-cell therapy....

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Vydáno v:Oncoimmunology
Hlavní autoři: Van Caeneghem, Yasmine, De Munter, Stijn, Tieppo, Paola, Goetgeluk, Glenn, Weening, Karin, Verstichel, Greet, Bonte, Sarah, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Debets, Reno, Vermijlen, David, Abken, Hinrich, Vandekerckhove, Bart
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384408/
https://ncbi.nlm.nih.gov/pubmed/28405508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1283460
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