Regulatory B cells promote graft-versus-host disease prevention and maintain graft-versus-leukemia activity following allogeneic bone marrow transplantation

Regulatory B cells (Bregs) are involved in the pathogenesis of graft-versus-host disease (GVHD). However, whether Bregs can alleviate acute GVHD without compromising graft-versus-leukemia (GVL) effects remains unclear. Here, we evaluated the role of Bregs in acute GVHD and GVL activity in both a mou...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Hu, Yue, He, Gan-Lin, Zhao, Xiang-Yu, Zhao, Xiao-Su, Wang, Yu, Xu, Lan-Ping, Zhang, Xiao-Hui, Yu, Xue-Zhong, Liu, Kai-Yan, Chang, Ying-Jun, Huang, Xiao-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384367/
https://ncbi.nlm.nih.gov/pubmed/28405514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1284721
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