A CD3/CD28 microbead-based HIV-1 viral outgrowth assay

AIMS: Latently infected resting CD4 T cells represent a major barrier to HIV-1 eradication efforts. The standard assays used for measuring this reservoir induce activation of resting CD4 T cells with either phytohaemagglutinin (PHA) with irradiated feeder cells, or with anti-CD3 antibodies. We desig...

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Detalhes bibliográficos
Publicado no:J Virus Erad
Main Authors: Kuzmichev, Yury V, Veenhuis, Rebecca T, Pohlmeyer, Christopher W, Garliss, Caroline C, Walker-Sperling, Victoria EK, Blankson, Joel N
Formato: Artigo
Idioma:Inglês
Publicado em: Mediscript Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384271/
https://ncbi.nlm.nih.gov/pubmed/28435692
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