The Effect of Latency Reversal Agents on Primary CD8 + T Cells: Implications for Shock and Kill Strategies for Human Immunodeficiency Virus Eradication

Shock and kill strategies involving the use of small molecules to induce viral transcription in resting CD4 + T cells (shock) followed by immune mediated clearance of the reactivated cells (kill), have been proposed as a method of eliminating latently infected CD4 + T cells. The combination of the h...

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Foilsithe in:EBioMedicine
Main Authors: Walker-Sperling, Victoria E., Pohlmeyer, Christopher W., Tarwater, Patrick M., Blankson, Joel N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919475/
https://ncbi.nlm.nih.gov/pubmed/27428432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.04.019
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