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Break-induced telomere synthesis underlies alternative telomere maintenance
Homology-directed DNA repair is essential for genome maintenance through templated DNA synthesis. Alternative lengthening of telomeres (ALT) necessitates homology-directed DNA repair to maintain telomeres in about 10–15% of human cancers. How DNA damage induces assembly and execution of a DNA replic...
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| Publicat a: | Nature |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5384111/ https://ncbi.nlm.nih.gov/pubmed/27760120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20099 |
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