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In vivo imaging of DNA double-strand break induced telomere mobility during alternative lengthening of telomeres

Repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) requires mobilization of chromatin for homology searches that allow interaction of the sequence to be repaired and its template DNA. Here we describe a system to rapidly induce DSBs at telomeres and track their movement, as w...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Cho, Nam Woo, Lampson, Michael A., Greenberg, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378164/
https://ncbi.nlm.nih.gov/pubmed/27491801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.07.010
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