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Interchromosomal Homology Searches Drive Directional ALT Telomere Movement and Synapsis
Telomere length maintenance is a requisite feature of cellular immortalization and a hallmark of human cancer. While most human cancers express telomerase activity, approximately 10-15% employ a recombination-dependent telomere maintenance pathway known as Alternative Lengthening of Telomeres (ALT)...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4177039/ https://ncbi.nlm.nih.gov/pubmed/25259924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.08.030 |
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