A carregar...

dATF4 regulation of mitochondrial folate-mediated one-carbon metabolism is neuroprotective

Neurons rely on mitochondria as their preferred source of energy. Mutations in PINK1 and PARKIN cause neuronal death in early-onset Parkinson's disease (PD), thought to be due to mitochondrial dysfunction. In Drosophila pink1 and parkin mutants, mitochondrial defects lead to the compensatory up...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Celardo, Ivana, Lehmann, Susann, Costa, Ana C, Loh, Samantha HY, Miguel Martins, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384021/
https://ncbi.nlm.nih.gov/pubmed/28211874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.158
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!