Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway

Necroptosis is a form of necrotic cell death that requires the activity of the death domain-containing kinase RIP1 and its family member RIP3. Necroptosis occurs when RIP1 is deubiquitinated to form a complex with RIP3 in cells deficient in the death receptor adapter molecule FADD or caspase-8. Necr...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Schock, Suruchi N, Chandra, Neha V, Sun, Yuefang, Irie, Takashi, Kitagawa, Yoshinori, Gotoh, Bin, Coscoy, Laurent, Winoto, Astar
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384020/
https://ncbi.nlm.nih.gov/pubmed/28060376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.153
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