The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region

Ionotropic glutamate receptors (iGluRs) are responsible for most of the fast excitatory communication between neurons in our brain. The GluD2 receptor is a puzzling member of the iGluR family: It is involved in synaptic plasticity, plays a role in human diseases, e.g. ataxia, binds glycine and D-ser...

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Publicado en:Sci Rep
Autores principales: Tapken, Daniel, Steffensen, Thomas Bielefeldt, Leth, Rasmus, Kristensen, Lise Baadsgaard, Gerbola, Alexander, Gajhede, Michael, Jørgensen, Flemming Steen, Olsen, Lars, Kastrup, Jette Sandholm
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384001/
https://ncbi.nlm.nih.gov/pubmed/28387240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46145
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