Granulocyte colony-stimulating factor mobilizes dormant hematopoietic stem cells without proliferation in mice

Granulocyte colony-stimulating factor (G-CSF) is used clinically to treat leukopenia and to enforce hematopoietic stem cell (HSC) mobilization to the peripheral blood (PB). However, G-CSF is also produced in response to infection, and excessive exposure reduces HSC repopulation capacity. Previous wo...

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Udgivet i:Blood
Main Authors: Bernitz, Jeffrey M., Daniel, Michael G., Fstkchyan, Yesai S., Moore, Kateri
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Plenary Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383874/
https://ncbi.nlm.nih.gov/pubmed/28179275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-752923
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