Effects of Granulocyte Colony Stimulating Factor on Monosomy 7 Aneuploidy in Healthy Hematopoietic Stem Cell and Granulocyte Donors

BACKGROUND: Reports of monosomy 7 in patients receiving granulocyte colony stimulating factor (G-CSF) have raised concerns that this cytokine may promote genomic instability. However, there are no studies addressing whether repeated administration of G-CSF produces monosomy 7 aneuploidy in healthy d...

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Auteurs principaux: Olnes, Matthew J., Poon, Andrea, Miranda, Susan J., Pfannes, Loretta, Tucker, Zachary, Loeliger, Kelsey, Padilla-Nash, Hesed, Yau, Yu Ying, Ried, Thomas, Leitman, Susan F., Young, Neal S., Sloand, Elaine M.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235244/
https://ncbi.nlm.nih.gov/pubmed/21883270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2011.03313.x
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