Á lódáil...
Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia
In cell and animal models, telomere erosion promotes chromosomal instability via breakage-fusion-bridge cycles, contributing to the early stages of tumorigenesis. However, evidence involving short telomeres in cancer development in humans is scarce, epidemiologic, and indirect. Here we directly impl...
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| Main Authors: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169071/ https://ncbi.nlm.nih.gov/pubmed/22005790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.272 |
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