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Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization

We isolated hematopoietic stem cells (HSC) from mice treated with cyclophosphamide (CY) and granulocyte colony-stimulating factor (G-CSF). All mobilized multipotent progenitor activity was contained in two populations: Thy-1(lo)Sca-1(+)Lin(−)Mac-1(−)CD4(−)c-kit(+) long-term reconstituting progenitor...

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Detalhes bibliográficos
Main Authors: Morrison, Sean J., Wright, Douglas E., Weissman, Irving L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20016/
https://ncbi.nlm.nih.gov/pubmed/9050878
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