Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization

We isolated hematopoietic stem cells (HSC) from mice treated with cyclophosphamide (CY) and granulocyte colony-stimulating factor (G-CSF). All mobilized multipotent progenitor activity was contained in two populations: Thy-1(lo)Sca-1(+)Lin(−)Mac-1(−)CD4(−)c-kit(+) long-term reconstituting progenitor...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Morrison, Sean J., Wright, Douglas E., Weissman, Irving L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20016/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9050878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.5.1908
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