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Expansion of FasL-Expressing CD5(+) B Cells in Type 1 Diabetes Patients
Fas ligand drives insulitis in the non-obese diabetic mouse model of type 1 diabetes (T1D) and negatively regulates IL-10-producing (IL-10(pos)) CD5(+) B cells in pancreata. Relevance of these phenomena to the human disease is poorly understood. Here, using splenocytes from T1D, autoantibody (Ab(+))...
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| Pubblicato in: | Front Immunol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5383713/ https://ncbi.nlm.nih.gov/pubmed/28439273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00402 |
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