Protection from Autoimmune Diabetes and T-Cell Lymphoproliferation Induced by FasL Mutation Are Differentially Regulated and Can Be Uncoupled Pharmacologically

Spontaneous mutation of Fas (lpr) or FasL (gld) completely protects nonobese diabetic mice from autoimmune diabetes but also causes massive double-negative T-cell lymphoproliferation. In this study, we used bone marrow chimeras and adoptive transfer analysis to investigate further the role of FasL i...

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Bibliografische gegevens
Hoofdauteurs: Mohamood, Abdiaziz S., Guler, Mehmet L., Xiao, Zuoxiang, Zheng, Dongfeng, Hess, Allan, Wang, Yi, Yagita, Hideo, Schneck, Jonathan P., Hamad, Abdel Rahim A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941609/
https://ncbi.nlm.nih.gov/pubmed/17591957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070148
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