Effects of CYP2C19 Genetic Polymorphisms on PK/PD Responses of Omeprazole in Korean Healthy Volunteers

The aim of this study was to examine the effects of CYP2C19*2 and *3 genetic polymorphisms on omeprazole pharmacokinetic (PK) and pharmacodynamic (PD) responses. Twenty-four healthy Korean volunteers were enrolled and given 20 mg omeprazole orally once daily for 8 days. The genotypes of CYP2C19 sing...

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Gepubliceerd in:J Korean Med Sci
Hoofdauteurs: Park, Sunny, Hyun, Yang Jin, Kim, Yu Ran, Lee, Ju Hyun, Ryu, Sunae, Kim, Jeong Mi, Oh, Woo-Yong, Na, Han Sung, Lee, Jong Gu, Seo, Doo Won, Hwang, In Yeong, Park, Zewon, Jang, In-Jin, Oh, Jaeseong, Choi, Seung Eun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Korean Academy of Medical Sciences 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383603/
https://ncbi.nlm.nih.gov/pubmed/28378544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2017.32.5.729
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