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Influence of CYP2D6 Polymorphism on the Pharmacokinetic/Pharmacodynamic Characteristics of Carvedilol in Healthy Korean Volunteers
BACKGROUND: Carvedilol is commonly used to treat hypertension as a β- and α(1)-adrenoreceptor blocker, but it is metabolized by CYP2D6, and CYP2D6(*)10 allele is dominant in Asian population. The objective of this study was to assess the influence of CYP2D6 polymorphisms on the pharmacokinetic (PK)...
Zapisane w:
| Wydane w: | J Korean Med Sci |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Korean Academy of Medical Sciences
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6021360/ https://ncbi.nlm.nih.gov/pubmed/29962926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2018.33.e182 |
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