Broad TCR Repertoire And Diverse Structural Solutions To Recognition Of An Immunodominant CD8 T Cell Epitope

A keystone of antiviral immunity is CD8 T-cell recognition of viral peptides bound to MHC-I proteins. The recognition mode of individual T cell receptors (TCRs) has been studied in some detail, but how TCR variation functions in providing a robust response to viral antigen is unclear. The influenza...

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Vydáno v:Nat Struct Mol Biol
Hlavní autoři: Song, InYoung, Gil, Anna, Mishra, Rabinarayan, Ghersi, Dario, Selin, Liisa K., Stern, Lawrence J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383516/
https://ncbi.nlm.nih.gov/pubmed/28250417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3383
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