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Atg7 deficiency intensifies inflammasome activation and pyroptosis in Pseudomonas sepsis

Sepsis is a severe and complicated syndrome symbolized by dysregulation of host inflammatory responses and organ failure with high morbidity and mortality. The literature implies that autophagy is a crucial regulator of inflammation in sepsis. Here, we report that autophagy-related protein 7 (Atg7)...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Pu, Qinqin, Gan, Changpei, Li, Rongpeng, Li, Yi, Tan, Shirui, Li, Xuefeng, Wei, Yuquan, Lan, Lefu, Deng, Xin, Liang, Haihua, Ma, Feng, Wu, Min
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382979/
https://ncbi.nlm.nih.gov/pubmed/28258192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601196
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