Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy

Alzheimer’s disease is characterized by the combined presence of amyloid plaques and tau pathology, the latter being correlated with the progression of clinical symptoms. Neuroinflammatory changes are thought to be major contributors to Alzheimer’s disease pathophysiology, even if their precise role...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Laurent, Cyril, Dorothée, Guillaume, Hunot, Stéphane, Martin, Elodie, Monnet, Yann, Duchamp, Marie, Dong, Yuan, Légeron, François-Pierre, Leboucher, Antoine, Burnouf, Sylvie, Faivre, Emilie, Carvalho, Kévin, Caillierez, Raphaëlle, Zommer, Nadège, Demeyer, Dominique, Jouy, Nathalie, Sazdovitch, Veronique, Schraen-Maschke, Susanna, Delarasse, Cécile, Buée, Luc, Blum, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382942/
https://ncbi.nlm.nih.gov/pubmed/27818384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww270
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