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Progress of antibody-based inhibitors of the HGF–cMET axis in cancer therapy

Dysregulated receptor tyrosine kinase signaling in human cancer cells leads to tumor progression, invasion and metastasis. The receptor tyrosine kinase cMET is frequently overexpressed in cancer tissue, and activation of cMET signaling is related to drug resistance and the processes of carcinogenesi...

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Bibliografski detalji
Izdano u:Exp Mol Med
Glavni autori: Kim, Ki-Hyun, Kim, Hyori
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382561/
https://ncbi.nlm.nih.gov/pubmed/28336955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.17
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