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Progress of antibody-based inhibitors of the HGF–cMET axis in cancer therapy
Dysregulated receptor tyrosine kinase signaling in human cancer cells leads to tumor progression, invasion and metastasis. The receptor tyrosine kinase cMET is frequently overexpressed in cancer tissue, and activation of cMET signaling is related to drug resistance and the processes of carcinogenesi...
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| Publié dans: | Exp Mol Med |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5382561/ https://ncbi.nlm.nih.gov/pubmed/28336955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.17 |
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