Genotoxicity and acute and subchronic toxicity studies of a bioactive polyoxometalate in Wistar rats

BACKGROUND: Cs(2)K(4)Na [SiW(9)Nb(3)O(40)] (POM93) is a novel broad-spectrum antiviral agent with high activity, high stability, and low toxicity in vitro. Most toxicity studies for POM93 have been performed in cultured cell lines rather than in animals. Like other POMs, there is a lack of evidence...

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Udgivet i:BMC Pharmacol Toxicol
Main Authors: Qu, Xiaofeng, Xu, Kun, Zhao, Chao, Song, Xiuling, Li, Jinhua, Li, Li, Nie, Wei, Bao, Hao, Wang, Juan, Niu, Fenglan, Li, Juan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382445/
https://ncbi.nlm.nih.gov/pubmed/28381296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0133-x
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