Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease

Alterations of the dopaminergic (DAergic) system are frequently reported in Alzheimer's disease (AD) patients and are commonly linked to cognitive and non-cognitive symptoms. However, the cause of DAergic system dysfunction in AD remains to be elucidated. We investigated alterations of the midb...

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Published in:Nat Commun
Main Authors: Nobili, Annalisa, Latagliata, Emanuele Claudio, Viscomi, Maria Teresa, Cavallucci, Virve, Cutuli, Debora, Giacovazzo, Giacomo, Krashia, Paraskevi, Rizzo, Francesca Romana, Marino, Ramona, Federici, Mauro, De Bartolo, Paola, Aversa, Daniela, Dell'Acqua, Maria Concetta, Cordella, Alberto, Sancandi, Marco, Keller, Flavio, Petrosini, Laura, Puglisi-Allegra, Stefano, Mercuri, Nicola Biagio, Coccurello, Roberto, Berretta, Nicola, D'Amelio, Marcello
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382255/
https://ncbi.nlm.nih.gov/pubmed/28367951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14727
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