Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease

Alterations of the dopaminergic (DAergic) system are frequently reported in Alzheimer's disease (AD) patients and are commonly linked to cognitive and non-cognitive symptoms. However, the cause of DAergic system dysfunction in AD remains to be elucidated. We investigated alterations of the midb...

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Publicat a:Nat Commun
Autors principals: Nobili, Annalisa, Latagliata, Emanuele Claudio, Viscomi, Maria Teresa, Cavallucci, Virve, Cutuli, Debora, Giacovazzo, Giacomo, Krashia, Paraskevi, Rizzo, Francesca Romana, Marino, Ramona, Federici, Mauro, De Bartolo, Paola, Aversa, Daniela, Dell'Acqua, Maria Concetta, Cordella, Alberto, Sancandi, Marco, Keller, Flavio, Petrosini, Laura, Puglisi-Allegra, Stefano, Mercuri, Nicola Biagio, Coccurello, Roberto, Berretta, Nicola, D'Amelio, Marcello
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382255/
https://ncbi.nlm.nih.gov/pubmed/28367951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14727
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