Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease

Alterations of the dopaminergic (DAergic) system are frequently reported in Alzheimer's disease (AD) patients and are commonly linked to cognitive and non-cognitive symptoms. However, the cause of DAergic system dysfunction in AD remains to be elucidated. We investigated alterations of the midb...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Nobili, Annalisa, Latagliata, Emanuele Claudio, Viscomi, Maria Teresa, Cavallucci, Virve, Cutuli, Debora, Giacovazzo, Giacomo, Krashia, Paraskevi, Rizzo, Francesca Romana, Marino, Ramona, Federici, Mauro, De Bartolo, Paola, Aversa, Daniela, Dell'Acqua, Maria Concetta, Cordella, Alberto, Sancandi, Marco, Keller, Flavio, Petrosini, Laura, Puglisi-Allegra, Stefano, Mercuri, Nicola Biagio, Coccurello, Roberto, Berretta, Nicola, D'Amelio, Marcello
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382255/
https://ncbi.nlm.nih.gov/pubmed/28367951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14727
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