A carregar...
Mutational Analysis at Intersubunit Interfaces of an Anionic Glutamate Receptor Reveals a Key Interaction Important for Channel Gating by Ivermectin
The broad-spectrum anthelmintic drug ivermectin (IVM) activates and stabilizes an open-channel conformation of invertebrate chloride-selective glutamate receptors (GluClRs), thereby causing a continuous inflow of chloride ions and sustained membrane hyperpolarization. These effects suppress nervous...
Na minha lista:
| Publicado no: | Front Mol Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5382172/ https://ncbi.nlm.nih.gov/pubmed/28428744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00092 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|