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Subunit stoichiometry and arrangement in a heteromeric glutamate-gated chloride channel

The invertebrate glutamate-gated chloride-selective receptors (GluClRs) are ion channels serving as targets for ivermectin (IVM), a broad-spectrum anthelmintic drug used to treat human parasitic diseases like river blindness and lymphatic filariasis. The native GluClR is a heteropentamer consisting...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Degani-Katzav, Nurit, Gortler, Revital, Gorodetzki, Lilach, Paas, Yoav
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747773/
https://ncbi.nlm.nih.gov/pubmed/26792524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423753113
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