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NF-κB Signaling Pathway and its Potential as a Target for Therapy in Lymphoid Neoplasms
The NF-κB pathway, a critical regulator of apoptosis, plays a key role in many normal cellular functions. Genetic alterations and other mechanisms leading to constitutive activation of the NF-κB pathway contribute to cancer development, progression and therapy resistance by activation of downstream...
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| Veröffentlicht in: | Blood Rev |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5382109/ https://ncbi.nlm.nih.gov/pubmed/27773462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2016.10.001 |
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