Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury

Extracellular nucleic acids are proinflammatory molecules that have been implicated in a diverse range of diseases. We report here the development of a multivalent nucleic acid scavenging nanoprobe, where the fluorochrome thiazole orange (TO) is conjugated to a polymeric 40 kDa dextran carrier. Dext...

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Bibliographic Details
Published in:Theranostics
Main Authors: Chen, Howard H., Yuan, Hushan, Cho, Hoonsung, Feng, Yan, Ngoy, Soeun, Kumar, Anand T. N., Liao, Ronglih, Chao, Wei, Josephson, Lee, Sosnovik, David E.
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381246/
https://ncbi.nlm.nih.gov/pubmed/28382156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.17366
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