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Molecular MRI of Acute Necrosis with a Novel DNA-Binding Gadolinium Chelate: Kinetics of Cell Death and Clearance in Infarcted Myocardium: Huang et al: Molecular MRI of Acute Necrosis
BACKGROUND: Current techniques to image cell death in the myocardium are largely non-specific. Here we report the use of a novel DNA-binding gadolinium chelate (Gd-TO) to specifically detect the exposed DNA in acutely necrotic (ruptured) cells in vivo. METHODS AND RESULTS: In vivo MRI was performed...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370828/ https://ncbi.nlm.nih.gov/pubmed/21836081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCIMAGING.111.966374 |
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