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Cytoprotective Nanoparticles By Conjugation of a Polyhis Tagged Annexin V to a Nanoparticle Drug

We synthesized a cytoprotective magnetic nanoparticle by reacting a maleimide functionalized Feraheme (FH) with a disulfide linked dimer of a polyhis tagged annexin V. Following reductive cleavage of disulfide, the resulting annexin-nanoparticle (diameter = 28.0±2.0 nm by laser light scattering, 7.6...

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Detalhes bibliográficos
Publicado no:Nanoscale
Main Authors: Chen, Howard H., Yuan, Hushan, Cho, Hoonsung, Sosnovik, David E., Josephson, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312233/
https://ncbi.nlm.nih.gov/pubmed/25572921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4nr06861k
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