Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression

BACKGROUND: Gout is one of the common inflammatory arthritis which affects many people for inflicting unbearable pain. Macrophage-mediated inflammation plays an important role in gout. The uptake of monosodium urate (MSU) crystals by macrophages can lead to activation of NOD-like receptors containin...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Liu, Hai-Jiao, Pan, Xiu-Xiu, Liu, Bing-Qian, Gui, Xuan, Hu, Liang, Jiang, Chun-Yi, Han, Yuan, Fan, Yi-Xin, Tang, Yu-Lin, Liu, Wen-Tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381065/
https://ncbi.nlm.nih.gov/pubmed/28376889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0849-y
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