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The role of the NLRP3 inflammasome in gout

Gout is an inflammatory arthritis characterized by abrupt self-limiting attacks of inflammation caused by precipitation of monosodium urate crystals (MSU) in the joint. Recent studies suggest that orchestration of the MSU-induced inflammatory response is dependent on the proinflammatory cytokine IL-...

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Bibliographic Details
Main Authors: Kingsbury, Sarah R, Conaghan, Philip G, McDermott, Michael F
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218743/
https://ncbi.nlm.nih.gov/pubmed/22096368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S11330
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