Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control

Myeloma is heterogeneous at the molecular level with subgroups of patients characterised by features of epigenetic dysregulation. Outcomes for myeloma patients have improved over the past few decades except for molecularly defined high-risk patients who continue to do badly. Novel therapeutic approa...

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Bibliografiske detaljer
Udgivet i:Blood Cancer J
Main Authors: Pawlyn, C, Bright, M D, Buros, A F, Stein, C K, Walters, Z, Aronson, L I, Mirabella, F, Jones, J R, Kaiser, M F, Walker, B A, Jackson, G H, Clarke, P A, Bergsagel, P L, Workman, P, Chesi, M, Morgan, G J, Davies, F E
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380911/
https://ncbi.nlm.nih.gov/pubmed/28362441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2017.27
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