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Rhodium(i)-catalyzed stereoselective [4+2] cycloaddition of oxetanols with alkynes through C(sp(3))–C(sp(3)) bond cleavage

An efficient and convenient synthesis of highly functionalized dihydropyrans has been achieved through rhodium(i)-catalysed tandem C(sp(3))–C(sp(3)) bond cleavage and annulation of oxetanols with alkynes. An enantioselective version was enabled using a Binaphine ligand. Excellent site-selectivity an...

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Pubblicato in:Chem Sci
Autori principali: Guo, Rui, Zheng, Xinxin, Zhang, Dayong, Zhang, Guozhu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380880/
https://ncbi.nlm.nih.gov/pubmed/28451367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc05246k
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