Impact of germline and somatic missense variations on drug binding sites

Advancements in next-generation sequencing (NGS) technologies are generating a vast amount of data. This exacerbates the current challenge of translating NGS data into actionable clinical interpretations. We have comprehensively combined germline and somatic nonsynonymous single-nucleotide variation...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Yan, C, Pattabiraman, N, Goecks, J, Lam, P, Nayak, A, Pan, Y, Torcivia-Rodriguez, J, Voskanian, A, Wan, Q, Mazumder, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380835/
https://ncbi.nlm.nih.gov/pubmed/26810135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2015.97
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