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Distribution bias analysis of germline and somatic single-nucleotide variations that impact protein functional site and neighboring amino acids
Single nucleotide variations (SNVs) can result in loss or gain of protein functional sites. We analyzed the effects of SNVs on enzyme active sites, ligand binding sites, and various types of post translational modification (PTM) sites. We found that, for most types of protein functional sites, the S...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5296879/ https://ncbi.nlm.nih.gov/pubmed/28176830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42169 |
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