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Cytosine Methylation Affects the Mutability of Neighboring Nucleotides in Germline and Soma
Methylated cytosines deaminate at higher rates than unmethylated cytosines, and the lesions they produce are repaired less efficiently. As a result, methylated cytosines are mutational hotspots. Here, combining rare polymorphism and base-resolution methylation data in humans, Arabidopsis thaliana, a...
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| Publicado no: | Genetics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7153944/ https://ncbi.nlm.nih.gov/pubmed/32079595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303028 |
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