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14-3-3σ Contributes to Radioresistance by Regulating DNA Repair and Cell Cycle via PARP1 and CHK2

14-3-3σ has been implicated in the development of chemo and radiation resistance and in poor prognosis of multiple human cancers. While it has been postulated that 14-3-3σ contributes to these resistances via inhibiting apoptosis and arresting cells in G2/M phase of the cell cycle, the molecular bas...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Chen, Yifan, Li, Zhaomin, Dong, Zizheng, Beebe, Jenny, Yang, Ke, Fu, Liwu, Zhang, Jian-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380477/
https://ncbi.nlm.nih.gov/pubmed/28087741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0366
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