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14-3-3σ regulation of and interaction with YAP1 in acquired gemcitabine resistance via promoting ribonucleotide reductase expression

Gemcitabine is an important anticancer therapeutics approved for treatment of several human cancers including locally advanced or metastatic pancreatic ductal adenocarcinoma (PDAC). Its clinical effectiveness, however, is hindered by existence of intrinsic and development of acquired resistances. Pr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qin, Li, Dong, Zizheng, Zhang, Jian-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951245/
https://ncbi.nlm.nih.gov/pubmed/26894857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7394
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