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14-3-3σ regulation of and interaction with YAP1 in acquired gemcitabine resistance via promoting ribonucleotide reductase expression

Gemcitabine is an important anticancer therapeutics approved for treatment of several human cancers including locally advanced or metastatic pancreatic ductal adenocarcinoma (PDAC). Its clinical effectiveness, however, is hindered by existence of intrinsic and development of acquired resistances. Pr...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Qin, Li, Dong, Zizheng, Zhang, Jian-Ting
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951245/
https://ncbi.nlm.nih.gov/pubmed/26894857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7394
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