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Imexon enhances gemcitabine cytotoxicity by inhibition of ribonucleotide reductase
PURPOSE: Gemcitabine (GEM) is currently the standard first line treatment for pancreatic cancer; however, the overall survival of patients with this disease remains poor. Imexon is a pro-oxidant small molecule which produced a high response rate in combination with GEM in a phase I trial in pancreat...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987536/ https://ncbi.nlm.nih.gov/pubmed/20339847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1306-0 |
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