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Effects of G6pc2 Deletion on Body Weight and Cholesterol in Mice

Genome wide association study (GWAS) data have linked the G6PC2 gene to variations in fasting blood glucose (FBG). G6PC2 encodes an islet-specific glucose-6-phosphatase catalytic subunit that forms a substrate cycle with the beta cell glucose sensor glucokinase. This cycle modulates the glucose sens...

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Bibliografiske detaljer
Udgivet i:J Mol Endocrinol
Main Authors: Boortz, Kayla A., Syring, Kristen E., Pound, Lynley D., Mo, Huan, Bastarache, Lisa, Oeser, James K., McGuinness, Owen P., Denny, Joshua C., O’Brien, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380368/
https://ncbi.nlm.nih.gov/pubmed/28122818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-16-0202
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