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Continuum Electrostatics Approaches to Calculating pK(a)s and E(m)s in Proteins

Proteins change their charge state through protonation and redox reactions as well as through binding charged ligands. The free energy of these reactions are dominated by solvation and electrostatic energies and modulated by protein conformational relaxation in response to the ionization state chang...

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Detaylı Bibliyografya
Yayımlandı:Methods Enzymol
Asıl Yazarlar: Gunner, MR, Baker, Nathan A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380367/
https://ncbi.nlm.nih.gov/pubmed/27497160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.05.052
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