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Continuum Electrostatics Approaches to Calculating pK(a)s and E(m)s in Proteins

Proteins change their charge state through protonation and redox reactions as well as through binding charged ligands. The free energy of these reactions are dominated by solvation and electrostatic energies and modulated by protein conformational relaxation in response to the ionization state chang...

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Sparad:
Bibliografiska uppgifter
I publikationen:Methods Enzymol
Huvudupphovsmän: Gunner, MR, Baker, Nathan A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380367/
https://ncbi.nlm.nih.gov/pubmed/27497160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.05.052
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